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Complete identification of E-selectin ligand activity on neutrophils reveals a dynamic interplay and distinct functions of PSGL-1, ESL-1 and CD44

The selectins and their ligands are required for leukocyte extravasation during inflammation. Several glycoproteins have been suggested to bind to E-selectin in vitro but the complete identification of its physiological ligands has remained elusive. Here, we show using gene- and RNA-targeted loss-of...

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Detalhes bibliográficos
Main Authors: Hidalgo, Andrés, Peired, Anna J., Wild, Martin, Vestweber, Dietmar, Frenette, Paul S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4080624/
https://ncbi.nlm.nih.gov/pubmed/17442598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2007.03.011
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