Temporal Changes in Prevalence of Molecular Markers Mediating Antimalarial Drug Resistance in a High Malaria Transmission Setting in Uganda

Standard therapy for malaria in Uganda changed from chloroquine to chloroquine + sulfadoxine-pyrimethamine in 2000, and artemether-lumefantrine in 2004, although implementation of each change was slow. Plasmodium falciparum genetic polymorphisms are associated with alterations in drug sensitivity. W...

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Autori principali: Mbogo, George W., Nankoberanyi, Sheila, Tukwasibwe, Stephen, Baliraine, Frederick N., Nsobya, Samuel L., Conrad, Melissa D., Arinaitwe, Emmanuel, Kamya, Moses, Tappero, Jordan, Staedke, Sarah G., Dorsey, Grant, Greenhouse, Bryan, Rosenthal, Philip J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society of Tropical Medicine and Hygiene 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4080569/
https://ncbi.nlm.nih.gov/pubmed/24799371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4269/ajtmh.13-0647
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