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Rational combination of dual PI3K/mTOR blockade and Bcl-2/-xL inhibition in AML
Acute myeloid leukemia (AML) continues to represent an area of critical unmet need with respect to new and effective targeted therapies. The Bcl-2 family of pro- and antiapoptotic proteins stands at the crossroads of cellular survival and death, and the expression of and interactions between these p...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Physiological Society
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4080281/ https://ncbi.nlm.nih.gov/pubmed/24824212 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00173.2013 |
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