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Notch pathway inhibition controls myeloma bone disease in the murine MOPC315.BM model
Despite evidence that deregulated Notch signalling is a master regulator of multiple myeloma (MM) pathogenesis, its contribution to myeloma bone disease remains to be resolved. Notch promotes survival of human MM cells and triggers human osteoclast activity in vitro. Here, we show that inhibition of...
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| 主要な著者: | , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2014
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4080208/ https://ncbi.nlm.nih.gov/pubmed/24927406 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bcj.2014.37 |
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