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Altered amyloid precursor protein processing regulates glucose uptake and oxidation in cultured rodent myotubes
AIMS/HYPOTHESIS: Impaired glucose uptake in skeletal muscle is an important contributor to glucose intolerance in type 2 diabetes. The aspartate protease, beta-site APP-cleaving enzyme 1 (BACE1), a critical regulator of amyloid precursor protein (APP) processing, modulates in vivo glucose disposal a...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Springer Berlin Heidelberg
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4079947/ https://ncbi.nlm.nih.gov/pubmed/24849570 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-014-3269-x |
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