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Dysferlin regulates cell membrane repair by facilitating injury-triggered acid sphingomyelinase secretion
Dysferlin deficiency compromises the repair of injured muscle, but the underlying cellular mechanism remains elusive. To study this phenomenon, we have developed mouse and human myoblast models for dysferlinopathy. These dysferlinopathic myoblasts undergo normal differentiation but have a deficit in...
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| Auteurs principaux: | , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4079937/ https://ncbi.nlm.nih.gov/pubmed/24967968 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.272 |
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