Whole-genome sequencing of clarithromycin resistant Helicobacter pylori characterizes unidentified variants of multidrug resistant efflux pump genes

BACKGROUND: Clarithromycin (CLR) is the key drug in eradication therapy of Helicobacter pylori (H. pylori) infection, and widespread use of CLR has led to an increase in primary CLR-resistant H. pylori. The known mechanism of CLR resistance has been established in A2146G and A2147G mutations in the...

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Main Authors: Iwamoto, Akira, Tanahashi, Toshihito, Okada, Rina, Yoshida, Yukio, Kikuchi, Kaoru, Keida, Yoshihide, Murakami, Yoshiki, Yang, Lin, Yamamoto, Koji, Nishiumi, Shin, Yoshida, Masaru, Azuma, Takeshi
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2014
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4079918/
https://ncbi.nlm.nih.gov/pubmed/24995043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1757-4749-6-27
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