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Accumulation, internalization and therapeutic efficacy of neuropilin-1-targeted liposomes

Advancements in liposomal drug delivery have produced long circulating and very stable drug formulations. These formulations minimize systemic exposure; however, unfortunately, therapeutic efficacy has remained limited due to the slow diffusion of liposomal particles within the tumor and limited rel...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Paoli, Eric E., Ingham, Elizabeth S., Zhang, Hua, Mahakian, Lisa M., Fite, Brett Z., Gagnon, M. Karen, Tam, Sarah, Kheirolomoom, Azadeh, Cardiff, Robert D., Ferrara, Katherine W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4079909/
https://ncbi.nlm.nih.gov/pubmed/24434424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2014.01.005
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