Dynamic Contrast Enhanced MRI Detects Changes in Vascular Transport Rate Constants Following Treatment with Thermally-Sensitive Liposomal Doxorubicin

Temperature-sensitive liposomal formulations of chemotherapeutics, such as doxorubicin, can achieve locally high drug concentrations within a tumor and tumor vasculature while maintaining low systemic toxicity. Further, doxorubicin delivery by temperature-sensitive liposomes can reliably cure local...

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Detalhes bibliográficos
Publicado no:J Control Release
Main Authors: Fite, Brett Z., Kheirolomoom, Azadeh, Foiret, Josquin L., Seo, Jai W., Mahakian, Lisa M., Ingham, Elizabeth S., Tam, Sarah M., Borowsky, Alexander D., Curry, Fitz-Roy E., Ferrara, Katherine W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5545100/
https://ncbi.nlm.nih.gov/pubmed/28395970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2017.04.007
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