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Immunosuppressive myeloid cells induced by chemotherapy attenuate antitumor CD4+ T cell responses through the PD-1/PD-L1 axis

In recent years, immune-based therapies have become an increasingly attractive treatment option for patients with cancer. Cancer immunotherapy is often used in combination with conventional chemotherapy for synergistic effects. The alkylating agent cyclophosphamide (CTX) has been included in various...

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Dettagli Bibliografici
Autori principali: Ding, Zhi-Chun, Lu, Xiaoyun, Yu, Miao, Lemos, Henrique, Huang, Lei, Chandler, Phillip, Liu, Kebin, Walters, Matthew, Krasinski, Antoni, Mack, Matthias, Blazar, Bruce R., Mellor, Andrew L., Munn, David H., Zhou, Gang
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4079842/
https://ncbi.nlm.nih.gov/pubmed/24780756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-3596
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