Clinical hypothermia temperatures increase complement activation and cell destruction via the classical pathway

BACKGROUND: Therapeutic hypothermia is a treatment modality that is increasingly used to improve clinical neurological outcomes for ischemia-reperfusion injury-mediated diseases. Antibody-initiated classical complement pathway activation has been shown to contribute to ischemia-reperfusion injury in...

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Main Authors: Shah, Tushar A, Mauriello, Clifford T, Hair, Pamela S, Sandhu, Amandeep, Stolz, Michael P, Bass, William Thomas, Krishna, Neel K, Cunnion, Kenji M
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2014
Ábhair:
Research
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4079622/
https://ncbi.nlm.nih.gov/pubmed/24962100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-12-181
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