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Integrated Analysis of Mutation Data from Various Sources Identifies Key Genes and Signaling Pathways in Hepatocellular Carcinoma

BACKGROUND: Recently, a number of studies have performed genome or exome sequencing of hepatocellular carcinoma (HCC) and identified hundreds or even thousands of mutations in protein-coding genes. However, these studies have only focused on a limited number of candidate genes, and many important mu...

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Detalhes bibliográficos
Main Authors: Zhang, Yuannv, Qiu, Zhaoping, Wei, Lin, Tang, Ruqi, Lian, Baofeng, Zhao, Yingjun, He, Xianghuo, Xie, Lu
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4079600/
https://ncbi.nlm.nih.gov/pubmed/24988079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0100854
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