The cell wall components peptidoglycan and lipoteichoic acid from Staphylococcus aureus act in synergy to cause shock and multiple organ failure.

Although the incidence of Gram-positive sepsis has risen strongly, it is unclear how Gram-positive organisms (without endotoxin) initiate septic shock. We investigated whether two cell wall components from Staphylococcus aureus, peptidoglycan (PepG) and lipoteichoic acid (LTA), can induce the inflam...

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Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	De Kimpe, S J, Kengatharan, M, Thiemermann, C, Vane, J R
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 1995
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC40796/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7479784/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.22.10359
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