Loss of Urokinase Receptor Sensitizes Cells to DNA Damage and Delays DNA Repair

DNA damage induced by numerous exogenous or endogenous factors may have irreversible consequences on the cell leading to cell cycle arrest, senescence and cell death. The DNA damage response (DDR) is powerful signaling machinery triggered in response to DNA damage, to provide DNA damage recognition,...

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Hauptverfasser: Narayanaswamy, Pavan B., Hodjat, Mahshid, Haller, Hermann, Dumler, Inna, Kiyan, Yulia
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4079571/
https://ncbi.nlm.nih.gov/pubmed/24987841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0101529
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