Hepatitis C virus clearance correlates with HLA-DR expression on proliferating CD8+ T-cells in immune-primed chimpanzees

Vaccination of chimpanzees against hepatitis C virus (HCV) using T-cell based vaccines targeting non-structural proteins have not resulted in the same levels of control and clearance as those seen in animals re-exposed after HCV clearance. We hypothesized that the outcome of infection depends on the...

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Bibliographic Details
Main Authors: Zubkova, Iryna, Duan, Hongying, Wells, Frances, Mostowski, Howard, Chang, Esther, Pirollo, Kathleen, Krawczynski, Kris, Lanford, Robert, Major, Marian
Format: Artigo
Language:Inglês
Published: 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4079472/
https://ncbi.nlm.nih.gov/pubmed/24123114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.26747
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