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Antibodies to an interfering epitope in hepatitis C virus E2 can mask vaccine‐induced neutralizing activity

Hepatitis C virus (HCV) neutralization occurring at the E2 region 412‐426 (EP‐I) could be enhanced when antibodies directed specifically to the E2 region 434‐446 (EP‐II) were removed from serum samples of persistently infected patients and vaccinated chimpanzees, a phenomenon of so‐called antibody i...

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Detalhes bibliográficos
Publicado no:Hepatology
Main Authors: Kachko, Alla, Frey, Sharon E., Sirota, Lev, Ray, Ranjit, Wells, Frances, Zubkova, Iryna, Zhang, Pei, Major, Marian E.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4681649/
https://ncbi.nlm.nih.gov/pubmed/26251214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.28108
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