Clinical Utility of Simultaneous Quantitation of 25-Hydroxyvitamin D and 24,25-Dihydroxyvitamin D by LC-MS/MS Involving Derivatization With DMEQ-TAD

CONTEXT: The discovery of hypercalcemic diseases due to loss-of-function mutations in 25-hydroxyvitamin D-24-hydroxylase has placed a new demand for sensitive and precise assays for 24,25-dihydroxyvitamin D [24,25-(OH)(2)D]. OBJECTIVE: We describe a novel liquid chromatography and tandem mass spectr...

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Bibliographic Details
Main Authors: Kaufmann, Martin, Gallagher, J. Christopher, Peacock, Munro, Schlingmann, Karl-Peter, Konrad, Martin, DeLuca, Hector F., Sigueiro, Rita, Lopez, Borja, Mourino, Antonio, Maestro, Miguel, St-Arnaud, René, Finkelstein, Joel S., Cooper, Donald P., Jones, Glenville
Format: Artigo
Language:Inglês
Published: Endocrine Society 2014
Subjects:
Endocrine Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4079315/
https://ncbi.nlm.nih.gov/pubmed/24670084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2013-4388
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