Decreased Conversion of 25-hydroxyvitamin D(3) to 24,25-dihydroxyvitamin D(3) Following Cholecalciferol Therapy in Patients with CKD

BACKGROUND AND OBJECTIVES: Elevated concentrations of fibroblast growth factor 23 (FGF23) are postulated to promote 25-hydroxyvitamin D (25[OH]D) insufficiency in CKD by stimulating 24-hydroxylation of this metabolite, leading to its subsequent degradation; however, prospective human studies testing...

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Bibliographic Details
Published in:Clin J Am Soc Nephrol
Main Authors: Stubbs, Jason R., Zhang, Shiqin, Friedman, Peter A., Nolin, Thomas D.
Format: Artigo
Language:Inglês
Published: American Society of Nephrology 2014
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4220759/
https://ncbi.nlm.nih.gov/pubmed/25183657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2215/CJN.03130314
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