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Lis1 Reduction Causes Tangential Migratory Errors in Mouse Spinal Cord
Mutations in human LIS1 cause abnormal neuronal migration and a smooth brain phenotype known as lissencephaly. Lis1(+/−) (Pafah1b1) mice show defective lamination in the cerebral cortex and hippocampal formation, whereas homozygous mutations result in embryonic lethality. Given that Lis1 is highly e...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4079006/ https://ncbi.nlm.nih.gov/pubmed/21935943 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cne.22768 |
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