A Proliferative Burst During Preadolescence Establishes the Final Cardiomyocyte Number

It is widely believed that perinatal cardiomyocyte terminal differentiation blocks cytokinesis, thereby causing binucleation and limiting regenerative repair after injury. This suggests that heart growth should occur entirely by cardiomyocyte hypertrophy during preadolescence when, in mice, cardiac...

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Detalhes bibliográficos
Main Authors: Naqvi, Nawazish, Li, Ming, Calvert, John W., Tejada, Thor, Lambert, Jonathan P., Wu, Jianxin, Kesteven, Scott H., Holman, Sara R., Matsuda, Torahiro, Lovelock, Joshua D., Howard, Wesley W., Iismaa, Siiri E., Chan, Andrea Y., Crawford, Brian H., Wagner, Mary B., Martin, David I. K., Lefer, David J., Graham, Robert M., Husain, Ahsan
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4078902/
https://ncbi.nlm.nih.gov/pubmed/24813607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.03.035
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