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Pressure overload by suprarenal aortic constriction in mice leads to left ventricular hypertrophy without c-Kit expression in cardiomyocytes

Animal models of pressure overload are valuable for understanding hypertensive heart disease. We characterised a surgical model of pressure overload-induced hypertrophy in C57BL/6J mice produced by suprarenal aortic constriction (SAC). Compared to sham controls, at one week post-SAC systolic blood p...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Nicks, Amy M., Kesteven, Scott H., Li, Ming, Wu, Jianxin, Chan, Andrea Y., Naqvi, Nawazish, Husain, Ahsan, Feneley, Michael P., Smith, Nicola J., Iismaa, Siiri E., Graham, Robert M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7501855/
https://ncbi.nlm.nih.gov/pubmed/32948799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-72273-3
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