β3-integrin–deficient mice are a model for Glanzmann thrombasthenia showing placental defects and reduced survival

β3 integrins have been implicated in a wide variety of functions, including platelet aggregation and thrombosis (αIIbβ3) and implantation, placentation, angiogenesis, bone remodeling, and tumor progression (αvβ3). The human bleeding disorder Glanzmann thrombasthenia (GT) can result from defects in t...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Hodivala-Dilke, Kairbaan M., McHugh, Kevin P., Tsakiris, Dimitrios A., Rayburn, Helen, Crowley, Denise, Ullman-Culleré, Mollie, Ross, F. Patrick, Coller, Barry S., Teitelbaum, Steven, Hynes, Richard O.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1999
Assuntos:	Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC407888/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9916135/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI5487
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