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Deletion of the fibrogen alpha-chain gene (FGA) causes congenital afibrogenemia

Congenital afibrinogenemia is a rare autosomal recessive disorder characterized by the complete absence of detectable fibrinogen. Uncontrolled bleeding after birth from the umbilical cord is common, and spontaneous intracerebral bleeding and splenic rupture can occur throughout life. Patients respon...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Neerman-Arbez, Marguerite, Honsberger, Ariane, Antonarakis, Stylianos E., Morris, Michael A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 1999
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC407887/
https://ncbi.nlm.nih.gov/pubmed/9916133
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