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Deletion of the fibrogen alpha-chain gene (FGA) causes congenital afibrogenemia

Congenital afibrinogenemia is a rare autosomal recessive disorder characterized by the complete absence of detectable fibrinogen. Uncontrolled bleeding after birth from the umbilical cord is common, and spontaneous intracerebral bleeding and splenic rupture can occur throughout life. Patients respon...

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Autores principales: Neerman-Arbez, Marguerite, Honsberger, Ariane, Antonarakis, Stylianos E., Morris, Michael A.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 1999
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC407887/
https://ncbi.nlm.nih.gov/pubmed/9916133
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