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Antigen expression level threshold tunes the fate of CD8 T cells during primary hepatic immune responses
CD8 T-cell responses to liver-expressed antigens range from deletional tolerance to full effector differentiation resulting in overt hepatotoxicity. The reasons for these heterogeneous outcomes are not well understood. To identify factors that govern the fate of CD8 T cells activated by hepatocyte-e...
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| Hauptverfasser: | , , , , , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4078818/ https://ncbi.nlm.nih.gov/pubmed/24927525 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1406674111 |
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