Novel Role for Tumor-Induced Expansion of Myeloid Derived Cells in Cancer Cachexia

Cancer progression is associated with inflammation, increased metabolic demand, infection, cachexia, and eventually, death. Myeloid-derived suppressor cells (MDSCs) commonly expand during cancer and are associated with adaptive immune suppression and inflammatory metabolite production. We propose th...

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Hauptverfasser: Cuenca, Alex G, Cuenca, Angela L, Winfield, Robert D, Joiner, Dallas N, Gentile, Lori, Delano, Matthew J, Kelly-Scumpia, Kindra M, Scumpia, Philip O, Matheny, Michael K, Scarpace, Philip J, Vila, Lizette, Efron, Philip A, LaFace, Drake M, Moldawer, Lyle L
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4078793/
https://ncbi.nlm.nih.gov/pubmed/24829407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1302895
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