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Oxidative stress causes enhanced endothelial cell injury in human heme oxygenase-1 deficiency

The first known human case of heme oxygenase-1 (HO-1) deficiency is presented in this report. The patient is a six-year-old boy with severe growth retardation. He has been suffering from persistent hemolytic anemia characterized by marked erythrocyte fragmentation and intravascular hemolysis, with p...

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Detalhes bibliográficos
Main Authors: Yachie, Akihiro, Niida, Yo, Wada, Taizo, Igarashi, Noboru, Kaneda, Hisashi, Toma, Tomoko, Ohta, Kazuhide, Kasahara, Yoshihito, Koizumi, Shoichi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1999
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC407858/
https://ncbi.nlm.nih.gov/pubmed/9884342
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