A novel leukocyte adhesion deficiency caused by expressed but nonfunctional β2 integrins Mac-1 and LFA-1

In the leukocyte adhesion deficiency (LAD)-1 syndrome, there is diminished expression of β2(CD18) integrins. This is caused by lesions in the β2-subunit gene and gives rise to recurrent bacterial infections, impaired pus formation, and poor wound healing. We describe a patient with clinical features...

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Vydáno v:	J Clin Invest
Hlavní autoři:	Hogg, Nancy, Stewart, Mairi P., Scarth, Sarah L., Newton, Rebecca, Shaw, Jacqueline M., Law, S.K. Alex, Klein, Nigel
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Clinical Investigation 1999
Témata:	Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC407855/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9884339/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI3312
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