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Genetic and intervention studies implicating complement C3 as a major target for the treatment of periodontitis()

Chronic periodontitis is induced by a dysbiotic microbiota and leads to inflammatory destruction of tooth-supporting connective tissue and bone. The third component of complement, C3, is a point of convergence of distinct complement activation mechanisms but its involvement in periodontitis was not...

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Detalhes bibliográficos
Main Authors: Maekawa, Tomoki, Abe, Toshiharu, Hajishengallis, Evlambia, Hosur, Kavita B., DeAngelis, Robert A., Ricklin, Daniel, Lambris, John D., Hajishengallis, George
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4078411/
https://ncbi.nlm.nih.gov/pubmed/24808362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1400569
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