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A comparison of three (67/68)Ga-labelled exendin-4 derivatives for β-cell imaging on the GLP-1 receptor: the influence of the conjugation site of NODAGA as chelator

BACKGROUND: Various diseases derive from pathologically altered β-cells. Their function can be increased, leading to hyperinsulinism, or decreased, resulting in diabetes. Non-invasive imaging of the β-cell-specific glucagon-like peptide receptor-1 (GLP-1R) would allow the assessment of both β-cell m...

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Hlavní autoři: Jodal, Andreas, Lankat-Buttgereit, Brigitte, Brom, Maarten, Schibli, Roger, Béhé, Martin
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4078388/
https://ncbi.nlm.nih.gov/pubmed/25006548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13550-014-0031-9
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