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Locked nucleic acid modified DNA enzymes targeting early growth response-1 inhibit human vascular smooth muscle cell growth

Smooth muscle cell (SMC) proliferation and migration are key processes that occur in the pathogenesis of atherosclerosis and post-angioplasty restenosis. In the present study, we designed locked nucleic acid (LNA)-modified DNAzymes targeting a specific region spanning the translational start site of...

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Autors principals: Fahmy, Roger G., Khachigian, Levon M.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2004
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC407826/
https://ncbi.nlm.nih.gov/pubmed/15107496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh543
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