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Vascular Smooth Muscle Cell Proliferation and Regrowth after Mechanical Injury in Vitro Are Egr-1/NGFI-A-Dependent

Smooth muscle cell (SMC) proliferation is a key event in renarrowing of blood vessels after balloon angioplasty. Mechanical injury imparted to the arterial wall in experimental models induces the expression of the immediate-early gene, egr-1. Egr-1 binds to and activates expression from the proximal...

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Autori principali: Santiago, Fernando S., Atkins, David G., Khachigian, Levon M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Investigative Pathology 1999
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866910/
https://ncbi.nlm.nih.gov/pubmed/10487847
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