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Mesodermal mesenchymal cells give rise to myofibroblasts, but not epithelial cells, in mouse liver injury

Hepatic stellate cells (HSCs) and portal fibroblasts (PFs) are believed to be the major source of myofibroblasts that participate in fibrogenesis via synthesis of proinflammatory cytokines and extracellular matrices. Previous lineage tracing studies using MesP1(Cre) and Rosa26lacZ(flox) mice demonst...

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Bibliographische Detailangaben
Hauptverfasser: Lua, Ingrid, James, David, Wang, Jiaohong, Wang, Kasper S., Asahina, Kinji
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4077971/
https://ncbi.nlm.nih.gov/pubmed/24488807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.27035
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