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Mesodermal mesenchymal cells give rise to myofibroblasts, but not epithelial cells, in mouse liver injury

Hepatic stellate cells (HSCs) and portal fibroblasts (PFs) are believed to be the major source of myofibroblasts that participate in fibrogenesis via synthesis of proinflammatory cytokines and extracellular matrices. Previous lineage tracing studies using MesP1(Cre) and Rosa26lacZ(flox) mice demonst...

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Detalhes bibliográficos
Main Authors: Lua, Ingrid, James, David, Wang, Jiaohong, Wang, Kasper S., Asahina, Kinji
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4077971/
https://ncbi.nlm.nih.gov/pubmed/24488807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.27035
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