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Physiologic and metabolic safety of butyrylcholinesterase gene therapy in mice
In continuing efforts to develop gene transfer of human butyrylcholinesterase (BChE) as therapy for cocaine addiction, we conducted wide-ranging studies of physiological and metabolic safety. For that purpose, mice were given injections of adeno-associated virus (AAV) vector or helper-dependent aden...
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| Main Authors: | , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2014
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4077905/ https://ncbi.nlm.nih.gov/pubmed/24892251 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2014.05.067 |
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