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Physiologic and metabolic safety of butyrylcholinesterase gene therapy in mice

In continuing efforts to develop gene transfer of human butyrylcholinesterase (BChE) as therapy for cocaine addiction, we conducted wide-ranging studies of physiological and metabolic safety. For that purpose, mice were given injections of adeno-associated virus (AAV) vector or helper-dependent aden...

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Detalhes bibliográficos
Main Authors: Murthy, Vishakantha, Gao, Yang, Geng, Liyi, LeBrasseur, Nathan, White, Tom, Parks, Robin J, Brimijoin, Stephen
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4077905/
https://ncbi.nlm.nih.gov/pubmed/24892251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2014.05.067
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