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Autophagy in non-small cell lung carcinogenesis: A positive regulator of antitumor immunosurveillance

In a mouse model of non-small cell lung carcinogenesis, we recently found that the inactivation of the essential autophagy gene Atg5 causes an acceleration of the early phases of oncogenesis. Thus, hyperplastic lesions and adenomas are more frequent at early stages after adenoviral delivery of Cre r...

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Autori principali: Rao, Shuan, Yang, Heng, Penninger, Josef M, Kroemer, Guido
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4077894/
https://ncbi.nlm.nih.gov/pubmed/24413089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.27643
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