The Rational Design of Specific Peptide Inhibitor against p38α MAPK at Allosteric-Site: A Therapeutic Modality for HNSCC

p38α is a significant target for drug designing against cancer. The overproduction of p38α MAPK promotes tumorigenesis in head and neck squamous cell carcinoma (HNSCC). The ATP binding and an allosteric site referred as DFG are the key sites of the p38α mitogen activated protein kinase (MAPK) exploi...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Gill, Kamaldeep, Nigam, Lokesh, Singh, Ratnakar, Kumar, Suresh, Subbarao, Naidu, Chauhan, Shyam Singh, Dey, Sharmistha
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4077802/
https://ncbi.nlm.nih.gov/pubmed/24983631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0101525
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars