Deletion of the Kv2.1 delayed rectifier potassium channel leads to neuronal and behavioral hyperexcitability

The Kv2.1 delayed rectifier potassium channel exhibits high-level expression in both principal and inhibitory neurons throughout the central nervous system, including prominent expression in hippocampal neurons. Studies of in vitro preparations suggest that Kv2.1 is a key yet conditional regulator o...

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Main Authors: Speca, David J., Ogata, Genki, Mandikian, Danielle, Bishop, Hannah I., Wiler, Steve W., Eum, Kenneth, Wenzel, H. Jürgen, Doisy, Emily T., Matt, Lucas, Campi, Katharine L., Golub, Mari S., Nerbonne, Jeanne M., Hell, Johannes W., Trainor, Brian C., Sack, Jon T., Schwartzkroin, Philip A., Trimmer, James S.
Format: Artigo
Language:Inglês
Published: 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4077602/
https://ncbi.nlm.nih.gov/pubmed/24494598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/gbb.12120
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