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Hindered aryl bromides for regioselective palladium-catalysed direct arylation at less favourable C5-carbon of 3-substituted thiophenes

The use of the congested aryl bromide 2-bromo-1,3-dichlorobenzene as coupling partner allows to modify the regioselectivity of the arylation of 3-substituted thiophene derivatives in favour of carbon C5. The coupling of this aryl bromide with a variety of 3-substituted thiophenes gave in all cases t...

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Hlavní autoři: Jin, Rongwei, Bheeter, Charles Beromeo, Doucet, Henri
Médium: Artigo
Jazyk:Inglês
Vydáno: Beilstein-Institut 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4077437/
https://ncbi.nlm.nih.gov/pubmed/24991274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.10.123
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