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Local transdermal delivery of phenylephrine to the anal sphincter muscle using microneedles

We propose pretreatment using microneedles to increase perianal skin permeability for locally targeted delivery of phenylephrine (PE), a drug that increases resting anal sphincter pressure to treat fecal incontinence. Microneedle patches were fabricated by micromolding poly-lactic-acid. Pre-treatmen...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Baek, Changyoon, Han, MeeRee, Min, Junghong, Prausnitz, Mark R., Park, Jung-Hwan, Park, Jungho
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4077336/
https://ncbi.nlm.nih.gov/pubmed/21586307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2011.05.004
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