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Major Role of γδ T Cells in the Generation of IL-17(+) Uveitogenic T Cells()

We show that in vitro activation of interphotoreceptor retinoid-binding protein (IRBP)-specific T cells from C57BL/6 mice immunized with an uveitogenic IRBP peptide (IRBP(1–20)) under TH17-polarizing conditions is associated with increased expansion of T cells expressing the γδ TCR. We also show tha...

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Autores principales: Cui, Yan, Shao, Hui, Lan, Chen, Nian, Hong, O'Brien, Rebecca L., Born, Willi K., Kaplan, Henry J., Sun, Deming
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4077214/
https://ncbi.nlm.nih.gov/pubmed/19542467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0900241
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