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Acute 7,12-dimethylbenz[a]anthracene exposure causes differential concentration-dependent follicle depletion and gene expression in neonatal rat ovaries

Chronic exposure to the polycyclic aromatic hydrocarbon 7,12-dimethylbenz[a]anthracene (DMBA), generated during combustion of organic matter including cigarette smoke, depletes all ovarian follicle types in the mouse and rat, and in vitro models mimic this effect. To investigate the mechanisms invol...

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Main Authors: Madden, Jill A., Hoyer, Patricia B., Devine, Patrick J., Keating, Aileen F.
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4077181/
https://ncbi.nlm.nih.gov/pubmed/24576726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2014.02.011
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