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Ice breaking in GPCR structural biology

G-protein-coupled receptors (GPCRs) are one of the most challenging targets in structural biology. To successfully solve a high-resolution GPCR structure, several experimental obstacles must be overcome, including expression, extraction, purification, and crystallization. As a result, there are only...

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Detalhes bibliográficos
Main Authors: Zhao, Qiang, Wu, Bei-li
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4077136/
https://ncbi.nlm.nih.gov/pubmed/22286917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2011.187
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