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Ubiquitin Proteasome System in Parkinson Disease: a keeper or a witness?
OBJECTIVE: The aim of this work was to evaluate the role of Ubiquitin-Proteasome System (UPS) on mitochondrial-driven alpha-synuclein (aSN) clearance in in vitro, ex vivo and in vivo Parkinson disease (PD) cellular models. METHOD: We used SH-SY5Y ndufa2 knock-down (KD) cells, PD cybrids and peripher...
Tallennettuna:
| Päätekijät: | , , , , , , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2012
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4077023/ https://ncbi.nlm.nih.gov/pubmed/22921536 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2012.08.008 |
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