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A Cybrid Cell Model for the Assessment of the Link Between Mitochondrial Deficits and Sporadic Parkinson’s Disease

Parkinson’s disease (PD) is a multifactorial and clinically complex age-related movement disorder. The cause of its most common form (sporadic PD, sPD) is unknown, but one prominent causal factor is mitochondrial dysfunction. Although several genetic- and toxin-based models have been developed along...

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Veröffentlicht in:Methods Mol Biol
Hauptverfasser: Arduíno, Daniela M., Esteves, A. Raquel, Swerdlow, Russell H., Cardoso, Sandra M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4612525/
https://ncbi.nlm.nih.gov/pubmed/25634293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-2288-8_31
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