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Quantification of the transporter substrate fexofenadine in cell lysates by LC-MS/MS

Drug-drug interactions at transporters present a significant and under-investigated clinical problem. Investigations of specific transporter functions and screening for potential drug-drug interactions, both in vitro and especially in vivo, will require validated experimental probes. Fexofenadine, a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Flynn, Colleen A., Alnouti, Yazen, Reed, Gregory A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4076838/
https://ncbi.nlm.nih.gov/pubmed/21766379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/rcm.5111
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