Endotrophin triggers adipose tissue fibrosis and metabolic dysfunction

We recently identified endotrophin as an adipokine with potent tumour-promoting effects. However, the direct effects of local accumulation of endotrophin in adipose tissue have not yet been studied. Here we use a doxycycline-inducible adipocyte-specific endotrophin overexpression model to demonstrat...

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Hauptverfasser: Sun, Kai, Park, Jiyoung, Gupta, Olga T., Holland, William L., Auerbach, Pernille, Zhang, Ningyan, Marangoni, Roberta Goncalves, Nicoloro, Sarah M., Czech, Michael P., Varga, John, Ploug, Thorkil, An, Zhiqiang, Scherer, Philipp E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4076823/
https://ncbi.nlm.nih.gov/pubmed/24647224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms4485
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