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Adipocyte-derived endotrophin promotes malignant tumor progression

Adipocytes represent a major cell type in the mammary tumor microenvironment and are important for tumor growth. Collagen VI (COL6) is highly expressed in adipose tissue, upregulated in the obese state, and enriched in breast cancer lesions and is a stimulator of mammary tumor growth. Here, we have...

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Detalhes bibliográficos
Main Authors: Park, Jiyoung, Scherer, Philipp E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3484450/
https://ncbi.nlm.nih.gov/pubmed/23041627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI63930
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