PKA-mediated Phosphorylation of ATR Promotes Recruitment of XPA to UV-induced DNA Damage

The melanocortin 1 receptor (MC1R), which signals through cAMP, is a melanocytic transmembrane receptor involved in pigmentation, adaptive tanning and melanoma resistance. We report MC1R-mediated or pharmacologically-induced cAMP signaling promotes nucleotide excision repair (NER) in a cAMP-dependen...

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Main Authors: Jarrett, Stuart G., Wolf Horrell, Erin M., Christian, Perry A., Vanover, Jillian C., Boulanger, Mary C., Zou, Yue, D’Orazio, John A.
格式: Artigo
語言:Inglês
出版: 2014
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4076709/
https://ncbi.nlm.nih.gov/pubmed/24950377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2014.05.030
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