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PKA-mediated Phosphorylation of ATR Promotes Recruitment of XPA to UV-induced DNA Damage
The melanocortin 1 receptor (MC1R), which signals through cAMP, is a melanocytic transmembrane receptor involved in pigmentation, adaptive tanning and melanoma resistance. We report MC1R-mediated or pharmacologically-induced cAMP signaling promotes nucleotide excision repair (NER) in a cAMP-dependen...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4076709/ https://ncbi.nlm.nih.gov/pubmed/24950377 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2014.05.030 |
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